Mitogen-activatedproteinkinase相关论文
Mitogen-activated protein kinase (MAPK) cas-cades are key signaling modules downstream of receptors/sensors that perceiv......
6-Gingerol protects against cardiac remodeling by inhibiting the p38 mitogen-activated protein kinas
6-Gingerol,a pungent ingredient of ginger,has been reported to possess anti-inflammatory and antioxidant activities,but ......
Gambogic Acid Induces Cell Apoptosis and Inhibits MAPK Pathway in PTEN-/-/p53-/-Prostate Cancer Cell
Objective:To investigate the effect of gambogic acid (GA) on the growth and cell death of castrate resistant prostate ca......
Enhancer of zeste homologue 2 simultaneously activates wnt and mitogen-activated protein kinase sign
As an alternative to genetic changes, epigenetic changes contribute to the aberrant activation of oncogenic signaling in......
Objective: Atherosclerosis is a common disease with severe morbidity and mortality,and many basic and clinical studies h......
Mitogen-activated protein kinase kinase 6-fusion protein (MAP2K6-FP) potentiates the anti-tumor effe
Objective: To investigate the antitumor effects of a mitogen-activated protein kinase (MAPK) kinase fusion protein,TAT-O......
JAK2 and MAPK pathways are involved in the inhibitory effect of berberine hydrochloride on gastric c
Aim This investigation was to identify whether Janusactivated kinase 2(JAK2) and mitogenactivated protein kinase (MAPK) ......
Epinephrine enhanced lipopolysaccharide-induced pro-inflammatory cytokine production in bone marrow-
Rationale and Objective Hormones, such as catecholamines, and pro-inflammatory cytokines were correlated with circadian ......
Objective: The purpose of this study was to investigate the effect of high glucose on apoptosis in human adipose tissue-......
Glioblastoma multiforme is the most prevalent type of primary brain tumor in adult humans, representing over 50% of adul......
Alcohol-related myopathy is characterized by severe biochemical and structural changes in skeletal muscle,and muscle at-......
Mitogen-activated protein kinases Inhibitors exerts anti-fibrosis by mediating TGF-β/ Smad signaling
Aims: To define further the mechanisms of TGF-β1/Smad signal transduction mediated by mitogen-activated protein kinases......
ERM protein moesin is phosphorylated by advanced glycation end products and modulates endothelial pe
Advanced glycation end products (AGEs) accumulated in different pathological conditions have the potent capacity to alte......
Advanced glycation end products induced oxidative stress by RAGE/MAPK signaling pathway in Human adi
Objective: Adipose tissue derived stem cell (ADSCs) transplantation has shown great promises for enhancing skin repair i......
Sildenafil,phosphodiesterase V inhibitors attenuate LPS-induced pro-inflammatory responses through d
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Dysfunction of human adipose tissue-derived stem cells induced by advanced glycation end products an
Objective To study the effects of advanced glycation end products-human serum albumin(AGEHSA) on the oxidative stress,pr......
Palmitic acid promotes endothelial progenitor cells apoptosis via p38 and JNK mitogen-activated prot
Objective Recent studies have demonstrated that palmitic acid(PA) could regulate endothelial progenitor cells(EPCs) func......
Follistatin-Like 1 Promotes Bleomycin-Induced Pulmonary Fibrosis through the Transforming Growth Fac
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Salvianolic Acid B Down-regulates Matrix Metalloproteinase-9 Activity and Expression in Tumor Necros
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Role of protein tyrosine kinase in IL-1β induced activation of mitogen-activated protein kinase in f
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The signal transduction pathway in the proliferation of airway smooth muscle cells induced by uroten
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Mitogen -activated protein kinase-dependent apoptosis in norcan-tharidin-treated A375-S2 cells is pr
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Mitogen-activated protein kinases (MAPKs) play pivotal roles in development and in interactions with the environment......
The fission yeast Schizosaccharomycespombeis an excellent model organism for the study of eukaryotic molecular and c......
The MAPK(mitogen-activated protein kinase)signaling pathway cascades are relativity conserved in eukaryotes,includin......
Effects of 4-nonylphenol isomers on cell receptors and mitogen-activatedprotein kinase pathway in mo
Technical nonylphenol contains at least 20 para-substituted isomers.It has beenshown that NP isomers vary in their e......
Involvement of mitogen-activated protein kinase pathways in N-methyl-D-aspartate-induced excitotoxic
Previous studies have shown that mitogen-activated protein kinase (MAPK) signaling pathways are involved in N-methyl-D-a......
Anti-parkinsonian effects of octacosanol in 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine-treated mic
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Mechanisms of extracellular signal-regulated kinase/cAMP response element-binding protein/brain-deri
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目的观察神经型尼古丁受体α3亚单位(α3nAChR)及丝裂原活化蛋白激酶(MAPK)信号通路中细胞外调节蛋白激酶(ERK1/2)、c-Jun氨基末端激酶(JN......
Increased expression of mitogen-activated protein kinase and its upstream regulating signal in human
AIM: To investigate the expression of mitogen-activated protein kinases (MAPKs) and its upstream protein kinase in human......
H pylori stimulates proliferation of gastric cancer cells through activating mitogen-activated prote
AIM: To explore the mechanism by which H pylori causes activation of gastric epithelial cells.METHODS: A VacA (+) and Ca......
Effects of Mitogen-activated Protein Kinase Signal Pathway on Heat Shock Protein 27 Expression in Hu
d that sodium salicylate can induce the expression of HSP27 in HLECs-B3. The effects are mediated, at least in part, thr......
Insulin induces PKC-dependent proliferation of mesenteric vascular smooth muscle cells from hyperten
Background and objectives Proliferation of human vascular smooth muscle cells (VSMCs) induced by hyperinsulinemia is a v......
目的 观察甲状旁腺激素(PTH)对人肾小管上皮细胞分泌结缔组织生长因子(CTGF)的影响,并探讨丝裂原活化蛋白激酶(MAPK)信号途径在此......